Pharmacogenomics Expert Witness

When faced with an unexpected drug outcome, the explanation often lies in an individual’s genomics, metabolism, or complex drug interactions. Dr. James Sonner, a Harvard-educated physician and former Professor of Anesthesiology at UCSF, provides rapid, case-focused pharmacogenomic analysis to help legal professionals determine causation, defensibility, and clear next steps.

Specialized Expertise in Genetic Drug Response

Attorneys frequently contact Dr. Sonner when dealing with a case that “doesn’t make sense,” where drug levels seem inconsistent, or a standard dose results in an unexpected overdose. You need straightforward answers grounded in pharmacology and genetics—not speculation. Dr. Sonner offers focused expertise in the following areas:

  • Pharmacogenomics & Pharmacogenetics: Analyzing how genetic variations affect individual drug metabolism and patient response.

  • Pharmacokinetics & Pharmacodynamics: Evaluating drug movement, absorption, and physiological effects, with specific expertise in opioids, anesthetics, and sedatives.

  • Drug-Drug Interactions: Assessing complex medication profiles to identify toxic combinations or metabolic inhibition.

  • Postmortem Toxicology: Interpreting postmortem drug levels in legal and forensic contexts to establish accurate timelines and causation.

    Professional Deliverables & Case Insight

    Dr. Sonner provides clear, actionable insights to help you build a fact-based legal strategy. Initial case reviews are fast, confidential, and frequently offered as a complimentary consultation to help attorneys quickly grasp the scientific merits of a claim. His deliverables include:

    Clear Causation Opinion

    A straightforward, jury-friendly explanation of what likely happened and the physiological or genetic mechanisms involved.

    Assessment of Case Strength

    An objective evaluation of causation strength to help you determine the viability and defensibility of the case.

    Identification of Key Issues

    Highlighting the critical pharmacological, metabolic, or genetic factors that will dictate the direction of the litigation.

    Academic Distinction Meets Clinical Reality

    As a board-certified anesthesiologist, Harvard Medical School graduate, and former UCSF Professor, Dr. Sonner bridges the gap between complex genetic data and real-world clinical outcomes. His extensive research background ensures that you receive an objective, science-driven analysis tailored to the unique facts of your case.

    Need a clear causation opinion grounded in genetics and pharmacology? Contact Dr. James Sonner today to request a FREE case review.

    Experience That Translates into Clarity and Credibility

    Dr. Sonner’s expertise stands apart through a combination of academic distinction and real-world clinical insight. Having treated thousands of patients and conducted extensive research on anesthetics and neurological drugs, he brings unparalleled depth of knowledge to each case.

    His ability to explain complex pharmacological mechanisms in accessible, fact-based terms ensures that decision-makers understand the nuances of every case. As a member of the American Society of Anesthesiologists, Dr. Sonner upholds the highest standards of professional integrity and precision.

    Facing inconsistent toxicology reports or an unexpected adverse drug reaction? Contact Dr. James Sonner today to discuss the scientific merits of your case.